Difference between revisions of "Improve Care for Babies Born Drug Dependent"

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=Introductory Paragraph=
=Introductory Paragraph=


Babies who are born with an opioid dependence experience discomfort and trauma.  They can scream and cry, have tremors, struggle with eating, and can struggle with being comforted. There are opportunities to help the babies while mothers, and the often overwhelmed and hospital staff that are trying to care for the babies and mothers. New approaches based on recent evidence-based research includes moving from NICU and pharmacology treatment to a mother-centered approach with eat, sleep, console. This approach emphasizes keeping the mother-infant dyad together in a calm setting while encouraging frequent feedings, comforting, and swaddling to treat Neonatal Abstinence Syndrome (NAS).<ref>http://www.advocatedocs.com/wp-content/uploads/2019/07/ESC-CBT.pdf</ref>
Babies who are born with an opioid dependence experience discomfort and trauma.  They may cry, scream, have tremors, and struggle with eating and with being comforted. Hospital staff are finding new opportunities to help these babies and their mothers. Approaches based on recent evidence-based research include moving from NICU and pharmacology treatment to a mother-centered approach. This keeps the mother-infant dyad together in a calm setting while encouraging frequent feedings, comforting, and swaddling to treat Neonatal Abstinence Syndrome (NAS).


= Key Information =
= Key Information =


Since the 1970s pharmacology has been the standard for treating babies born drug dependent or with Neo-natal abstinence syndrome (NAS) with a greater severity or exposure. Physicians have utilized methadone or morphine in treatment of NAS born babies.<ref>https://www.chcf.org/blog/opioid-dependent-newborns-get-new-treatment/</ref>  Traditionally infants born with drug dependent have been managed in the NICU to treat due to concerns of complications. The Finnegan Score/Finnegan Tool<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786483/</ref> has dictated the care level for babies born drug dependent.<ref> https://ncpoep.org/guidance-document/neonatal-abstinence-syndrome-overview/neonatal-abstinence-syndrome-nas/#:~:text=The%20Finnegan%20Neonatal%20Abstinence%20Scoring,Fletcher%20Allan%20Hospital%20of%20Vermont.</ref>
Since the 1970s, pharmacology has been the standard for treating babies born drug dependent or with NAS. Physicians have utilized Methadone or Morphine in treatment of babies with NAS. <ref>https://www.chcf.org/blog/opioid-dependent-newborns-get-new-treatment/</ref>  Traditionally infants born drug dependent have been managed in the NICU to treat due to concerns of complications. The Finnegan Score/Finnegan Tool has dictated the care level for babies born drug dependent. <ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786483/</ref> <ref>https://ncpoep.org/guidance-document/neonatal-abstinence-syndrome-overview/neonatal-abstinence-syndrome-nas/#:~:text=The%20Finnegan%20Neonatal%20Abstinence%20Scoring,Fletcher%20Allan%20Hospital%20of%20Vermont.</ref>


Treatment of infants showing signs of withdrawal includes supportive care approach to treatment and can include creating a dark and quiet environment, swaddling the infant to improve self-stimulation, and providing frequent feedings to reduce infant stress.
Complications from NAS can include: <ref>https://www.marchofdimes.org/complications/neonatal-abstinence-syndrome-(nas).aspx#</ref>
 
Other strategies include skin-to-skin contact for comfort and promotion of the infant’s attachment to the mother/caregiver, as well as other comforting techniques such as rocking or swaying the infant.  Frequent feedings address hydration level.  Educating families on methods of care is also important to provide ongoing supportive care of the infant.
 
Breastfeeding has been proven to also be an effective approach if the mother is receiving medication-assisted treatment and has no other complications that inhibit breastfeeding.
 
Complications from NAS can include<ref>https://www.marchofdimes.org/complications/neonatal-abstinence-syndrome-(nas).aspx#</ref>:


*Low birthweight
*Low birthweight
Line 27: Line 21:
*Vision problems
*Vision problems


Recent research has introduced a new approach to treatment of babies born drug dependent - Eat, Sleep, Console- which is a mother-center approach.<ref>  https://www.nichq.org/insight/mother-centered-approach-treating-neonatal-abstinence-syndrome</ref>
Treatment of infants showing signs of withdrawal includes a supportive care approach to treatment, such as creating a dark and quiet environment, swaddling the infant to improve self-stimulation, and providing frequent feedings to reduce infant stress. Other strategies include skin-to-skin contact for comfort and promotion of the infant’s attachment to the mother/caregiver, as well as other comforting techniques such as rocking or swaying the infant. Frequent feedings address hydration level. Breastfeeding has been proven to also be an effective approach if the mother is receiving medication-assisted treatment and has no other complications that inhibit breastfeeding. Educating families on methods of care is important to provide ongoing supportive care of the infant.
 
'''Eat, Sleep, Console (ESC) Model'''
 
Recent research has introduced the ESC approach to treatment of babies born drug dependent This is a mother-centered approach, based upon the following: <ref>  https://www.nichq.org/insight/mother-centered-approach-treating-neonatal-abstinence-syndrome</ref>
*Eat: Is the baby feeding normally?
*Eat: Is the baby feeding normally?
*Sleep: Is the baby able to sleep?
*Sleep: Is the baby able to sleep?
*Console: Can the baby be consoled within ten minutes of crying?
*Console: Can the baby be consoled within ten minutes of crying?


The Eat, Sleep, Console approach may be used alone or in conjunction with the Finnegan's model for scoring.  The simple components of the approach show a decrease in overall length of hospitalization as well as a decrease in need for a pharmacological approach.
The ESC approach may be used alone or in conjunction with the Finnegan's model for scoring.  The simple components of the approach have shown a decrease in overall length of hospitalization as well as a decrease in need for a pharmacological approach.


= Relevant Research =
= Relevant Research =
'''Eat, Sleep, Console Approach: A Family-Centered Model for the Treatment of Neonatal Abstinence Syndrome'''<ref>https://pubmed.ncbi.nlm.nih.gov/30855311/</ref>


'''A Novel Approach to Assessing Infants With Neonatal Abstinence Syndrome'''<ref>https://pubmed.ncbi.nlm.nih.gov/29263121/</ref>
'''This article''' is a literature review titled "Eat, Sleep, Console Approach: A Family-Centered Model for the Treatment of Neonatal Abstinence Syndrome." It is an evidenced-based practice brief that summarizes and critically review emerging research on the ESC method. <ref>https://pubmed.ncbi.nlm.nih.gov/30855311/</ref>


'''Impact of Parental Presence at Infants' Bedside on Neonatal Abstinence Syndrome'''<ref>https://www.semanticscholar.org/paper/Impact-of-Parental-Presence-at-Infants%27-Bedside-on-Howard-Schiff/9880e862e325f5e443091b2d6961488f65d62ac5</ref>
'''This research study''' compared treatment decisions of 50 consecutive opioid-exposed infants managed on the inpatient unit at the Yale New Haven Children's Hospital. Infants managed by using the ESC approach were treated with Morphine significantly less frequently than they would have been by using the Finnegan Neonatal Abstinence Scoring System assessment approach. The article is titled, "A Novel Approach to Assessing Infants With Neonatal Abstinence Syndrome." <ref>https://pubmed.ncbi.nlm.nih.gov/29263121/</ref>


'''Implementing the Eat, Sleep, Console Approach for NAS Management: Review of Literature'''<ref>https://openprairie.sdstate.edu/cgi/viewcontent.cgi?article=1115&context=con_dnp</ref>
'''This article''' documents the decreased impact of NAS associated with parental time spent at the infant's bedside.  <ref>https://www.semanticscholar.org/paper/Impact-of-Parental-Presence-at-Infants%27-Bedside-on-Howard-Schiff/9880e862e325f5e443091b2d6961488f65d62ac5</ref>
 
'''This literature review''' on ESC is part of a doctorate in nursing practice. It addresses:
*the need to improve NAS assessment practices
*the benefits of family-centered care
*the need to develop well-structured NAS treatment protocols. <ref>https://openprairie.sdstate.edu/cgi/viewcontent.cgi?article=1115&context=con_dnp</ref>


= Impactful Federal, State, and Local Policies =
= Impactful Federal, State, and Local Policies =
'''Substance Exposed Infants & States responses to the problem'''<ref>https://ncsacw.acf.hhs.gov/files/Substance-Exposed-Infants.pdf</ref>
 
'''The Comprehensive Addiction and Recovery Act (CARA) of 2016''' amended the  Child Abuse
and Prevention Treatment Act (CAPTA). This policy brief summarizes how states are required to serve infants and their families affected by prenatal substance exposure. It uses highlights form seven states to unpack the implications for notification and reporting requirements and for plans of safe care. <ref>https://ncsacw.acf.hhs.gov/files/prenatal-substance-exposure-brief1.pdf</ref>


=Available Tools & Resources=
=Available Tools & Resources=
'''Substance Exposed Infants & States Response to the Problem'''<ref>https://ncsacw.acf.hhs.gov/files/Substance-Exposed-Infants.pdf</ref>


'''Opioid-Dependent Newborns Get New Treatment: Mom Instead of Morphine'''<ref>https://www.chcf.org/blog/opioid-dependent-newborns-get-new-treatment/</ref>
'''Canadian Provincial Health Resources, British Columbia''' provides a practice resource for healthcare providers titled, "Care of the Newborn Exposed to Substances During Pregnancy." <ref>http://www.perinatalservicesbc.ca/Documents/Guidelines-Standards/Newborn/Practice%20Resource%20ESC_WEB%202020_11_20.pdf</ref>


'''Women & Infants Clinical Institute- Guide for Eat, Sleep & Console'''<ref>https://doh.wa.gov/sites/default/files/legacy/Documents/Pubs/CSH-ESCPlaybookElectronic.pdf</ref>
'''The Saskatchewan Health Authority''' created a handout on ESC for new parents. <ref>"Caring For Your Newborn At Risk For Substance Withdrawal with the Eat Sleep Console Method," https://momsandkidssask.saskhealthauthority.ca/sites/default/files/documents/esc-parent-handout.pdf</ref>


'''Webinar- NAS: The Eat, Sleep, Console Approach'''<ref>https://wvperinatal.org/event/webinar-nas-the-eat-sleep-console-approach/</ref>
'''The California Healthcare Foundation''' has a blog that details the benefits of ESC in a hihgly accessible manner. It is titled "Opioid-Dependent Newborns Get New Treatment: Mom Instead of Morphine." <ref>https://www.chcf.org/blog/opioid-dependent-newborns-get-new-treatment/</ref>


'''Caring for Opioid-Exposed Newborns Using the Eating, Sleeping, Consoling Care Toolkit''' ''A Downloadable Guide''<ref>https://docplayer.net/87738560-Caring-for-opioid-exposed-newborns-using-the-eating-sleeping-consoling-esc-care-tool.html</ref>
'''ESC Toolkit.''' This downloadable guidebook resulted from a collaboration between doctors at Boston University School of Medicine, Children’s Hospital at Dartmouth-Hitchcock, and Yale University School of Medicine. <ref>https://docplayer.net/87738560-Caring-for-opioid-exposed-newborns-using-the-eating-sleeping-consoling-esc-care-tool.html</ref>


'''Care of the Newborn Exposed to Substances During Pregnancy''' ''Practice Resources for Healthcare Providers'' <ref>http://www.perinatalservicesbc.ca/Documents/Guidelines-Standards/Newborn/Practice%20Resource%20ESC_WEB%202020_11_20.pdf</ref>
'''Yale School of Medicine.''' This webinar is provided by the originator of ESC -- Matthew Grossman, MD, Associate Professor of Pediatrics, Yale-New Haven Children’s Hospital. <ref>https://wvperinatal.org/event/webinar-nas-the-eat-sleep-console-approach/</ref>


'''Caring For Your Newborn At Risk For Substance Withdrawal with the Eat Sleep Console Method''' ''A handout for new parents''<ref>https://momsandkidssask.saskhealthauthority.ca/sites/default/files/documents/esc-parent-handout.pdf</ref>
'''Women & Infants Clinical Institute''' has published an ESC guidebook that includes recommendations, approaches, and resources. The guidebook was developed through collaboration between Bakersfield Memorial Hospital in California, CHI Franciscan in Tacoma, Washington, and the Yale-New Haven Children’s Hospital. <ref>https://doh.wa.gov/sites/default/files/legacy/Documents/Pubs/CSH-ESCPlaybookElectronic.pdf</ref>


'''Safe Project''' Addiction and Mental Health Resources for Women'''<ref>https://www.safeproject.us/resource/women/</ref>
'''Lily's Place''' is a neonatal withdrawal center that offers workshops and trainings on legislation to support NAS centers and on planning and funding a NAS center. <ref>http://www.lilysplace.org/presentations-and-workshops</ref>
 
'''SAFE Project''' has a dedicated website for Addiction and Mental Health Resources for Women that includes a number of support resources during and after pregnancy. <ref>https://www.safeproject.us/resource/women/</ref>


= Promising Practices =
= Promising Practices =


'''Eat, Sleep, Console (ESC) Model'''
'''Kentucky.''' In Louisville, healthcare workers are using a combination of pacifiers and music therapy to ease the pain of babies born to mothers who used opioids during their pregnancy. They use a special pressurized pacifier that plays music. A NICU music therapist uses music and live-singing, patting and rocking to match the baby's behavior state, ultimately training the child to soothe itself. This calming has improved feeding and sleeping and decrease their crying -- eliminating three of the major symptoms that lead babies to have to need medication or hospital stay. <ref>http://www.wmur.com/article/new-device-helps-tiniest-victims-of-the-opioid-crisis/10370051</ref>
Several hospitals are implementing the approach lead by Dr. Matthew Gossman of Yale-New Haven Children's Hospital.   The following hospitals put together a ESC playbook for information and implementation.
*Bakersfield Memorial Hospital, Bakersfield, California
*CHI Franciscan, Tacoma, Washington
*Yale-New Haven Children’s Hospital
 
The guide includes recommendations, approaches and resources.<ref>https://doh.wa.gov/sites/default/files/legacy/Documents/Pubs/CSH-ESCPlaybookElectronic.pdf</ref>


 
'''Maryland.''' The Maryland Patient Safety Center is working with 30 birthing centers to develop standardized care for babies suffering from NAS in order to reduce the length of stay for these babies. Standards include:
'''Programs for Volunteers to Cuddle Babies Experiencing Withdrawal'''
*A calming environment with little stimulation - quiet rooms and low lights
 
There are a growing number of programs that have volunteers come to the hospitals to cuddle the babies. This helps comfort the babies and reduces the stress on the nurses--two important benefits.
 
'''Magee-Womens Hospital "Cuddle the Crisis"
 
*At Magee-Womens Hospital of UPMC in Pennsylvania, volunteers are helping babies born addicted to opioids by cuddling, nurturing, and comforting the babies as they go through withdrawal.
*Cuddlers provide them with additional comfort, as opposed to having to start an IV or give a baby morphine <ref>https://www.insideedition.com/headlines/19669-hospital-recruits-volunteers-to-cuddle-with-drug-addicted-babies-going-through-withdrawal</ref>
Add more programs here with links to learn more.
 
'''Music Therapy'''
 
Using a combination of pacifiers and music therapy, healthcare workers are able to ease the pain of babies born to mothers who used opioids during their pregnancy. If you can improve babies feeding and sleeping, decrease their crying and make them more calm, then you've just eliminated three of the major symptoms that lead babies to have to need medication or hospital stay.
 
Components:
 
*A NICU music therapist uses music and live-singing, patting and rocking to match the baby's behavior state, ultimately training the child to soothe itself
*Use of special pressurized pacifier that plays music.<ref>http://www.wmur.com/article/new-device-helps-tiniest-victims-of-the-opioid-crisis/10370051</ref>
 
 
'''The Maryland Patient Safety Center''' is working with 30 birthing centers to come up with standardized care for babies suffering from NAS.  This standard of care is significantly reducing the length of stay for these babies.
 
Standards can vary from baby to baby, but should include:
 
*Creating a calming environment with little stimulation - quiet rooms and low lights
*Cuddle rooms where volunteers rock and soothe babies  
*Cuddle rooms where volunteers rock and soothe babies  
*Can use massage and music therapy  
*Massage and music therapy  
*Some medicine (morphine or methadone)  
*Some medicine (Morphine or Methadone)  
*Treat mother's addiction and mental health in conjunction with babies' treatment
*Treatment of mother's addiction and mental health in conjunction with babies' treatment
 
'''Neonatal Withdrawal Center'''
 
''Lily's Place''


<ref>http://www.lilysplace.org/ Lily's Place</ref>Lily's Place is the first nonprofit infant recovery center for provides services for parents and families struggling with addiction. The center is specifically designed for babies with NAS with small, quiet, dimly-lit nursery rooms and 24-hour nursing staff. Parents are trained to help their babies via therapeutic handling techniques and they learn CPR and basic child care as well as the specifics of NAS. Contact Lily's Place (304) 523-5459 <ref>http://www.lilysplace.org/presentations-and-workshops workshops and trainings</ref> including the following:
'''Pennsylvania.''' At Magee-Womens Hospital of UPMC, volunteers are helping babies born addicted to opioids by cuddling, nurturing, and comforting the babies as they go through withdrawal. Cuddlers provide them with additional comfort, as opposed to having to start an IV or give a baby Morphine. <ref>https://www.insideedition.com/headlines/19669-hospital-recruits-volunteers-to-cuddle-with-drug-addicted-babies-going-through-withdrawal</ref> There are a growing number of programs that have volunteers come to the hospitals to cuddle the babies. This helps comfort the babies and reduces the stress on the nurses--two important benefits.


*Legislation to support NAS centers
'''West Virginia.''' Lily's Place was the first nonprofit infant recovery center to provide services for parents and families struggling with addiction. The center is specifically designed for babies with NAS with small, quiet, dimly-lit nursery rooms and 24-hour nursing staff. Parents are trained to help their babies via therapeutic handling techniques and they learn CPR and basic child care as well as the specifics of NAS. <ref>http://www.lilysplace.org/ </ref>
*Pre-opening NAS Center Operations Planning
*Funding & fundraising for a NAS center


= Sources =
= Sources =


----
----

Latest revision as of 17:12, 19 January 2024

Introductory Paragraph

Babies who are born with an opioid dependence experience discomfort and trauma. They may cry, scream, have tremors, and struggle with eating and with being comforted. Hospital staff are finding new opportunities to help these babies and their mothers. Approaches based on recent evidence-based research include moving from NICU and pharmacology treatment to a mother-centered approach. This keeps the mother-infant dyad together in a calm setting while encouraging frequent feedings, comforting, and swaddling to treat Neonatal Abstinence Syndrome (NAS).

Key Information

Since the 1970s, pharmacology has been the standard for treating babies born drug dependent or with NAS. Physicians have utilized Methadone or Morphine in treatment of babies with NAS. [1] Traditionally infants born drug dependent have been managed in the NICU to treat due to concerns of complications. The Finnegan Score/Finnegan Tool has dictated the care level for babies born drug dependent. [2] [3]

Complications from NAS can include: [4]

  • Low birthweight
  • Jaundice
  • Seizures
  • Sudden infant death syndrome (also called SIDS).
  • Developmental delays
  • Motor problems
  • Behavior and learning problems
  • Speech and language problems
  • Sleep problems
  • Ear infections
  • Vision problems

Treatment of infants showing signs of withdrawal includes a supportive care approach to treatment, such as creating a dark and quiet environment, swaddling the infant to improve self-stimulation, and providing frequent feedings to reduce infant stress. Other strategies include skin-to-skin contact for comfort and promotion of the infant’s attachment to the mother/caregiver, as well as other comforting techniques such as rocking or swaying the infant. Frequent feedings address hydration level. Breastfeeding has been proven to also be an effective approach if the mother is receiving medication-assisted treatment and has no other complications that inhibit breastfeeding. Educating families on methods of care is important to provide ongoing supportive care of the infant.

Eat, Sleep, Console (ESC) Model

Recent research has introduced the ESC approach to treatment of babies born drug dependent This is a mother-centered approach, based upon the following: [5]

  • Eat: Is the baby feeding normally?
  • Sleep: Is the baby able to sleep?
  • Console: Can the baby be consoled within ten minutes of crying?

The ESC approach may be used alone or in conjunction with the Finnegan's model for scoring. The simple components of the approach have shown a decrease in overall length of hospitalization as well as a decrease in need for a pharmacological approach.

Relevant Research

This article is a literature review titled "Eat, Sleep, Console Approach: A Family-Centered Model for the Treatment of Neonatal Abstinence Syndrome." It is an evidenced-based practice brief that summarizes and critically review emerging research on the ESC method. [6]

This research study compared treatment decisions of 50 consecutive opioid-exposed infants managed on the inpatient unit at the Yale New Haven Children's Hospital. Infants managed by using the ESC approach were treated with Morphine significantly less frequently than they would have been by using the Finnegan Neonatal Abstinence Scoring System assessment approach. The article is titled, "A Novel Approach to Assessing Infants With Neonatal Abstinence Syndrome." [7]

This article documents the decreased impact of NAS associated with parental time spent at the infant's bedside. [8]

This literature review on ESC is part of a doctorate in nursing practice. It addresses:

  • the need to improve NAS assessment practices
  • the benefits of family-centered care
  • the need to develop well-structured NAS treatment protocols. [9]

Impactful Federal, State, and Local Policies

The Comprehensive Addiction and Recovery Act (CARA) of 2016 amended the Child Abuse and Prevention Treatment Act (CAPTA). This policy brief summarizes how states are required to serve infants and their families affected by prenatal substance exposure. It uses highlights form seven states to unpack the implications for notification and reporting requirements and for plans of safe care. [10]

Available Tools & Resources

Canadian Provincial Health Resources, British Columbia provides a practice resource for healthcare providers titled, "Care of the Newborn Exposed to Substances During Pregnancy." [11]

The Saskatchewan Health Authority created a handout on ESC for new parents. [12]

The California Healthcare Foundation has a blog that details the benefits of ESC in a hihgly accessible manner. It is titled "Opioid-Dependent Newborns Get New Treatment: Mom Instead of Morphine." [13]

ESC Toolkit. This downloadable guidebook resulted from a collaboration between doctors at Boston University School of Medicine, Children’s Hospital at Dartmouth-Hitchcock, and Yale University School of Medicine. [14]

Yale School of Medicine. This webinar is provided by the originator of ESC -- Matthew Grossman, MD, Associate Professor of Pediatrics, Yale-New Haven Children’s Hospital. [15]

Women & Infants Clinical Institute has published an ESC guidebook that includes recommendations, approaches, and resources. The guidebook was developed through collaboration between Bakersfield Memorial Hospital in California, CHI Franciscan in Tacoma, Washington, and the Yale-New Haven Children’s Hospital. [16]

Lily's Place is a neonatal withdrawal center that offers workshops and trainings on legislation to support NAS centers and on planning and funding a NAS center. [17]

SAFE Project has a dedicated website for Addiction and Mental Health Resources for Women that includes a number of support resources during and after pregnancy. [18]

Promising Practices

Kentucky. In Louisville, healthcare workers are using a combination of pacifiers and music therapy to ease the pain of babies born to mothers who used opioids during their pregnancy. They use a special pressurized pacifier that plays music. A NICU music therapist uses music and live-singing, patting and rocking to match the baby's behavior state, ultimately training the child to soothe itself. This calming has improved feeding and sleeping and decrease their crying -- eliminating three of the major symptoms that lead babies to have to need medication or hospital stay. [19]

Maryland. The Maryland Patient Safety Center is working with 30 birthing centers to develop standardized care for babies suffering from NAS in order to reduce the length of stay for these babies. Standards include:

  • A calming environment with little stimulation - quiet rooms and low lights
  • Cuddle rooms where volunteers rock and soothe babies
  • Massage and music therapy
  • Some medicine (Morphine or Methadone)
  • Treatment of mother's addiction and mental health in conjunction with babies' treatment

Pennsylvania. At Magee-Womens Hospital of UPMC, volunteers are helping babies born addicted to opioids by cuddling, nurturing, and comforting the babies as they go through withdrawal. Cuddlers provide them with additional comfort, as opposed to having to start an IV or give a baby Morphine. [20] There are a growing number of programs that have volunteers come to the hospitals to cuddle the babies. This helps comfort the babies and reduces the stress on the nurses--two important benefits.

West Virginia. Lily's Place was the first nonprofit infant recovery center to provide services for parents and families struggling with addiction. The center is specifically designed for babies with NAS with small, quiet, dimly-lit nursery rooms and 24-hour nursing staff. Parents are trained to help their babies via therapeutic handling techniques and they learn CPR and basic child care as well as the specifics of NAS. [21]

Sources


  1. https://www.chcf.org/blog/opioid-dependent-newborns-get-new-treatment/
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786483/
  3. https://ncpoep.org/guidance-document/neonatal-abstinence-syndrome-overview/neonatal-abstinence-syndrome-nas/#:~:text=The%20Finnegan%20Neonatal%20Abstinence%20Scoring,Fletcher%20Allan%20Hospital%20of%20Vermont.
  4. https://www.marchofdimes.org/complications/neonatal-abstinence-syndrome-(nas).aspx#
  5. https://www.nichq.org/insight/mother-centered-approach-treating-neonatal-abstinence-syndrome
  6. https://pubmed.ncbi.nlm.nih.gov/30855311/
  7. https://pubmed.ncbi.nlm.nih.gov/29263121/
  8. https://www.semanticscholar.org/paper/Impact-of-Parental-Presence-at-Infants%27-Bedside-on-Howard-Schiff/9880e862e325f5e443091b2d6961488f65d62ac5
  9. https://openprairie.sdstate.edu/cgi/viewcontent.cgi?article=1115&context=con_dnp
  10. https://ncsacw.acf.hhs.gov/files/prenatal-substance-exposure-brief1.pdf
  11. http://www.perinatalservicesbc.ca/Documents/Guidelines-Standards/Newborn/Practice%20Resource%20ESC_WEB%202020_11_20.pdf
  12. "Caring For Your Newborn At Risk For Substance Withdrawal with the Eat Sleep Console Method," https://momsandkidssask.saskhealthauthority.ca/sites/default/files/documents/esc-parent-handout.pdf
  13. https://www.chcf.org/blog/opioid-dependent-newborns-get-new-treatment/
  14. https://docplayer.net/87738560-Caring-for-opioid-exposed-newborns-using-the-eating-sleeping-consoling-esc-care-tool.html
  15. https://wvperinatal.org/event/webinar-nas-the-eat-sleep-console-approach/
  16. https://doh.wa.gov/sites/default/files/legacy/Documents/Pubs/CSH-ESCPlaybookElectronic.pdf
  17. http://www.lilysplace.org/presentations-and-workshops
  18. https://www.safeproject.us/resource/women/
  19. http://www.wmur.com/article/new-device-helps-tiniest-victims-of-the-opioid-crisis/10370051
  20. https://www.insideedition.com/headlines/19669-hospital-recruits-volunteers-to-cuddle-with-drug-addicted-babies-going-through-withdrawal
  21. http://www.lilysplace.org/